ECTS Organises Webinars on practical issues on Bone Muscle & Beyond topics, including basic and clinical research. These webinars feature prominent speakers and allow participants to ask questions regarding the latest information on relevant topics.
Registration is free for members and non-members.
Upcoming Live Webinars
Big Data, Omics, and the Need to Replicate
Featuring Prof. André Uitterlinden, Dept of Internal Medicine & Epidemiology, Erasmus MC, The Netherlands
and moderated by Nerea Alonso Lopez, Rheumatology and Bone Disease Unit, Centre for Genomic and Experimental Medicine, University of Edinburgh, United Kingdom
Date & Time: 18 January 2018, 4-5pm CET
Costs: free webinar for ECTS members and non-members, but a registration is required
- To become familiar with Big Data in Life Sciences, complex biology and Genomics/Genetics
- To understand a few examples of Technology and Big Omics Datasets
- To understand analytical challenges in big data analysis
- To understand the best way forward in obtaining robust results
Presenter: Prof. André Uitterlinden, Dept of Internal Medicine & Epidemiology, Erasmus MC, The Netherlands
André Uitterlinden is Professor of Complex Genetics at the Erasmus Medical Centre in Rotterdam – The Netherlands – where he holds positions in 3 departments: Internal Medicine, Epidemiology, and Clinical Chemistry.
His research is focusing on genetic factors for common traits and disease, including anthropometry, endocrine traits & disorders and locomotor disease such as osteoporosis and osteoarthritis. At Erasmus MC he is also head of one of Europe’s largest high-throughput DNA facility, providing services for DNA isolation, genotyping and sequencing.
As a PI (Personal Investigator) and member of the MT, he is coordinating all molecular genetic analyses in 2 major cohort studies at Erasmus MC: the Rotterdam Study (12,000 elderly subjects) and the Generation R birth-cohort (n=7,000 children +12,000 parents).
He is collaborating with many (large) international epidemiological study populations and coordinates the GEFOS consortium involving >150.000 subjects to identify genetic risk factors for osteoporosis. He is a member of the Research Steering Committee of the CHARGE consortium and was director of the Netherlands Consortium for Healthy Aging (NCHA).
He has published over 850 papers in refereed journals (H-index 116, source Web of Science); furthermore he is leading annual international well known courses on complex genetics at Erasmus MC in Rotterdam – The Netherlands.
Date & Time: 7 December 2017, 4-5pm CET
Costs: free webinar for ECTS members and non-members, but a registration is required
Join Alon Greenbaum (California Institute of Technology, CalTech) to hear about Bone CLARITY, a bone tissue clearing method that enables visualization of the physiological processes at the cellular level in an intact bone environment. During this one-hour session Alon will present his work and how he used Bone CLARITY to detect the endogenous fluorescence of Sox9-tdTomato+ osteoprogenitor cells in the tibia, femur, and vertebral column of adult transgenic mice.
Presenter: Alon Greenbaum, California Institute of Technology, CalTech
Alon holds his BS and MS degrees in Electrical Engineering from Tel Aviv University, and his Ph.D in Electrical Engineering from University of California, Los Angeles. In his doctoral degree, Alon conducted biophotonics research under Prof. Aydogan Ozcan, focusing on high-resolution and high-throughput microscopy for biomedical applications. In Prof. Viviana Gradinaru’s lab (California Institute of Technology), he is exploring innovative imaging techniques for various bone and neuroscience applications. Alon have been awarded the Good Ventures Postdoctoral Fellowship of the Life Sciences Research Foundation, as well as the Howard Hughes Medical Institute International Student Research Fellowship. Alon have published over 25 peer reviewed journal articles and his work has been presented in over 30 conferences.
Moderator: Nadia Rucci, University of L’Aquila, Italy
Nadia Rucci is Associate Professor and head of the Skeletal Diseases Laboratory (Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Italy). She graduated in Biology at “La Sapienza” University of Rome (Italy), then she moved to the University of L’Aquila, where she achieved her PhD in Endocrinology and Metabolic Diseases. Nadia Rucci’s research is mainly focused on oncologic (breast cancer induced bone metastases), metabolic (osteoporosis) and genetic (osteopetrosis) bone diseases. Nadia is currently PI of two projects: “Extracellular vesicles as new therapeutic approach to target bone tumour cells” funded by the Italian Association of Cancer Research and “Bone phenotype in Duchenne muscular dystrophy: unveiling the role of LCN2 and implications for therapy” funded by AFM-Telethon. She has published 63 original research articles in peer-review international journals.
Gut Microbiota – Regulation of Bone Mass
Date & Time: 12 October 2017, 16:00 – 17:00 CET
- To learn about possible mechanisms for the impact of the gut microbiota on bone mass.
- To understand challenges in preclinical research on gut microbiota and bone: how genetic background, age, diet, animal facility, sex and GM composition can impact the results.
- To critically evaluate the gut microbiota as a possible novel therapeutic target for osteoporosis and fracture prevention.
- To define probiotics and prebiotics and learn how changing the gut microbiota may impact bone.
- To understand the concept of transplantation of a beneficial faecal microbiota.
Presenter: Klara Sjögren, CBAR, University of Gothenburg
Klara Sjögren is Associate Professor in Molecular Medicine at the Centre for Bone and Arthritis Research at the Sahlgrenska Academy in Göteborg, Sweden. Her research focuses on connections between gut microbiota (GM) and bone mass and whether changes in GM could promote bone disease. She was the first to demonstrate that the gut microbiota regulates bone mass. Her research projects are translational and multidisciplinary connecting microbiology, endocrinology, immunology and bone metabolism and include cell cultures, experimental animal models and clinical trials.
Moderator: Thomas Funck-Brentano, CBAR, University of Gothenburg
Thomas Funck-Brentano is a clinical rheumatologist with a preclinical background. He is a member of the ECTS Academy since 2016. He trained in University Paris Diderot and defendend his PhD (supervised by Pr Martine Cohen-Solal) in 2013 on the role of the Wnt signaling pathway in the subchondral bone in preclinical models of osteoarthritis. He then was assistant professor in the department of Rheumatology in Hôpital Lariboisière in Paris (2012-2016) were he got particularly interested in managing bone diseases, such as osteoporosis and rare bone diseases. He has recently moved to the University of Gothenburg (Sweden) in Pr Claes Ohlsson’s group to enhance his skills in translational research. His project on the functional studies of NOTUM as a regulator of cortical bone mass was granted by Sweden’s Innovation Agency Vinnova for a two-year fellowship. He is also involved in clinical research projects on the link between bone and cardiometabolic diseases and osteoarthritis using various large databases.
Date & Time: 14 September 2017 from 4:00pm to 5:00pm CET
- Learn about the advantages/disadvantages of using liquid biopsies in the clinic
- Learn about the collection and use of liquid biopsies
- Learn about the content of liquid biopsies
- Learn about extraction methods of liquid biopsies
- Learn about miRNAs and their correlation with bone metabolism endpoints
Presenter: Matthias Hackl, CEO and co-founder, TAmiRNA GmbH
Matthias Hackl graduated in the area of Biotechnology from the University of Natural Resources and Life Sciences Vienna (Boku) in 2012. His studies of microRNA function in mammalian cell lines and model systems of Ageing involved rotations through labs at the University of Georgia and Minnesota in the United States as well as University Bielefeld in Germany. Matthias has won two private company grants for developing applications of PCR and Flow Cytometry based microRNA quantification tools and was honored by the Austrian Association of Molecular Life Sciences and Biotechnology for his achievements during his PhD. He has authored 30 publications and two book chapters in the field of microRNA biology and held a one-year PostDoc position in microRNA-based cell engineering at the Vienna Institute of Biotechnology before joining TAmiRNA. Matthias Hackl is also co-founder of Remute Bio GmbH, founded in 2016.
Moderator: Bram van der Eerden
Bram van der Eerden studied Biology in Utrecht (the Netherlands) and received his PhD in 2002 in Leiden (the Netherlands) working on the hormonal regulation of growth plate cartilage. Since then, he has been working within the department of Internal medicine of the Erasmus MC in Rotterdam on the role of calcium channels in bone and is now mainly involved in the functional characterization of novel compounds/genes/pathways that are anabolic to bone, using in vitro and in vivo models. Currently, he is group leader of the laboratory for Calcium and Bone Metabolism of Internal Medicine at the Erasmus MC. Bram has (co)-authored >50 peer-reviewed papers, has been board member of the Dutch Calcium and Bone Metabolism Society (NVCB) for 6 years and is now in the Bone networking group of the Dutch Society for Endocrinology. He was co-chair of the IBMS young investigator committee and is currently chairing the ECTS Webinar Committee. He has been involved in a number of international projects, including an ongoing Horizon2020 Marie-Curie Staff Exchange project (RUBICON) focusing on the molecular pathways in connective tissue diseases. His research group consists of 2 senior scientists, 1 Post-doc, 4 PhD students and 2 technicians.