|
Meet the Professor
Lawrence G. Raisz, MD
Pathogenesis of Osteoporosis: Concepts
and Prospects
Outline
- Major pathogenetic mechanisms
- Determinants of peak bone mass – genetics and lifestyle
- Determinants of accelerated bone loss – estrogen and calcium
deficiency
- Determinants of impaired formation response – cellular
aging and growth factor abnormalities
- Determinants for falls – drugs, neuromuscular impairment and
environment
- Areas of uncertainty – sites and mechanisms of estrogen action,
role of cytokines, roles of the Wnt signaling pathways.
Education goals
Attendees should be able to outline the major known pathogenetic
mechanisms in osteoporosis and define the most important unanswered questions
Target audience
Clinicians, clinical investigators and basic researchers interested in
studying the pathogenesis of osteoporosis.
Teaching method
The attendees will have a handout summarizing the major topics to be covered
and be asked to give the group their ideas concerning each topic as well
as having the opportunity to ask questions.
|
|
|
