|
Meet the Professor
André Uitterlinden
Genetics of Bone Diseases
Genetic analysis of bone diseases, in particular the complex
diseases such as osteoporosis, has made substantial progress through accomplishments
of the Human Genome project and its sequela (dbSNP, HapMap), and novel
technological developments. This workshop will address approaches, pitfalls
and progress in identifying genetic markers for bone diseases such as
osteoporosis.
Topics to be covered
- Study design (collections, populations, meta-analysis)
- Genotyping techniques (single SNPs, Genome Wide Approaches with high
density SNP arrays), DNA handling
- Examples of gene polymorphisms: associations, clinical use, functional
analysis
Key educational goals
- Learn and understand principles of genetic analysis
- Understand limitations of approaches
- Understand what approach should be taken to find bone genes
Target audience
This workshop is aimed at people at all levels: medical graduate students,
basic researchers (PhD student, postdocs, staff), technicians, clinical
investigators, practising clinicians.
Teaching methods
A brief overview of the field and the topics mentioned will be given,
allowing much space for questions from the audience. The discussion will
be informal and interactive.
|
|
|
