Abstracts
Programme at a glance
   

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Monday 12th May 2003

SYMPOSIUM 7

OSTEOPOROSIS TREATMENT

Chairs: G. Crepaldi (Padova, Italy)
R. Marcus (Stanford CA, USA)

09:00 I-32 Basic research strategies to identify new osteoporosis treatments
R. Baron (New Haven CT, USA)

09:30 I-33 New treatments, new trials, new paradigms for preventing fractures
S. Cummings (San Francisco CA, USA)

HOT TOPICS

Chairs: S. Cummings (San Francisco CA, USA)
G. A. Rodan (West Point PA, USA)

11:00 O-46 USE OF STATINS AND RISK OF VERTEBRAL FRACTURE
M. W. C. J. Schoofs^1,2*, M. van der Klift^2,1, C. E. D. H. de Laet³, A. Hofman¹, M. C. J. M. Sturkenboom¹, B. H. C. Stricker^1,2, H. A. P. Pols^2,1
1Department of Epidemiology & Biostatistics, Erasmus MC, Rotterdam, The Netherlands
²Department of Internal Medicine, Erasmus MC, Rotterdam, The Netherlands
³Department of Public Health, Erasmus MC, Rotterdam, The Netherlands

11:12 O-47 RELATIONSHIP BETWEEN LIPIDS AND BONE MASS IN HEALTHY WOMEN AND MEN
S. Adami*, V. Braga, D. Gatti, M. Rossini, J. Bakri, E. Battaglia
Rheumatological Rehabilitation, University Hospital Valeggio S/M, Italy

11:24 O-48 COMPARISON OF QUANTITATIVE ULTRASOUND AND DUAL-ENERGY X-RAY ABSORPTIOMETRY FOR THE PREDICTION OF CLINICAL FRACTURES IN OLDER WOMEN: THE OPUS STUDY
C. Glueer¹*, R. Eastell², D. M. Reid³, C. Roux⁴, D. Felsenberg⁵, R. Barkmann^1
1University Clinic Kiel, Germany
²University of Sheffield, UK
³University of Aberdeen, UK
⁴Rene Descartes University, Paris, France
⁵Benjamin Franklin Hospital Berlin, Germany

11:36 O-49 NITROGEN-CONTAINING BISPHOSPHONATES INDIRECTLY STIMULATE PROLIFERATION OF GAMMA,DELTA-T CELLS BY INHIBITING THE MEVALONATE PATHWAY
K. Thompson*, M. J. Rogers
Bone Research Group, University of Aberdeen, Aberdeen, UK

11:48 O-50 EXPRESSION OF NOVEL KINASE RDRAK1 IN OSTEOCLASTS AND ITS ROLE IN CLODRONATE INDUCED APOPTOSIS OF OSTEOCLASTS
T. Uemura^1,2*, H. Kojima^1,3, B. Liu^1,4, A. Nemoto^1,3, K. Kobatake^1,5, Y. K. Liu^4
1Age Dimension Research Center, AIST, Tsukuba, Japan
²Tokyo Med. Dent. Univ.,Tokyo, Japan
³JST, Tokyo, Japan
⁴Fudan Univ., Shanghai, P.R.China
⁵Tokyo Univ., Science, Chiba, Japan

12:00 O-51 CALCITRIOL THERAPY REDUCES FALLS AND FRACTURES IN ELDERLY WOMEN
J. C. Gallagher¹*, G. Haynatski¹, S. Fowler^2
1Creighton University, Omaha, NE, USA
²Biostatistics, George Washington University, Washington DC, USA

12:12 O-52 OSTEOPOROSIS IN MICE LACKING JUNB
L. Kenner¹*, A. Hoebertz¹, F. T. Beil², M. Amling², N. Keon³, A. Szremska¹, P. Angel³, M. Schorpp-Kistner³, M. Wagner^1
1Institute of Molecular Pathology, Dr. Bohrgasse, A-1030 Vienna, Austria
²Unfall- und Wiederherstellungschirurgie, University of Hamburg, Martinistrasse 52
³Deutsches Krebsforschungszentrum, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany

12:24 O-53 EFFECT OF REINFORCEMENT WITH BONE TURNOVER MARKER RESULTS ON PERSISTENCE WITH RISEDRONATE TREATMENT IN POSTMENOPAUSAL WOMEN WITH OSTEOPOROSIS: IMPROVING THE MEASUREMENTS OF PERSISTENCE ON ACTONEL TREATMENT (IMPACT) STUDY
P. D. Delmas¹*, B. Vrijens², L. van de Langerijt³, C. Roux⁴, R. Eastell⁵ J. D. Ringe⁶, H. A. P. Pols⁷, D. Cahall³, N .B. Watts^8
1INSERM Research Unit 403 and Claude Bernard University of Lyon, Lyon, France
²AARDEX Ltd, Vise, Belgium
³Aventis Pharmaceuticals, Bridgewater, New Jersey, USA
⁴Hopital Cochin, University Rene-Descartes, Paris, France
⁵University of Sheffield, Sheffield, UK
⁶Klinikum Leverkusen, University of Cologne, Leverkusen, Germany
⁷Erasmus University, Rotterdam, The Netherlands
⁸University of Cincinnati, Cincinnati, Ohio, USA

12:36 O-54 RISK-BENEFIT ASSESSMENT FOR RALOXIFENE: 4-YEAR DATA FROM THE MULTIPLE OUTCOMES OF RALOXIFENE EVALUATION (MORE) TRIAL
E. Barrett-Connor¹*, J. Cauley², P. Kulkarni³, A. Sashegyi³, D. Cox³, J. Geiger^3
1La Jolla, California, USA
²University of Pittsburgh, Pittsburgh, Pennsylvania, USA
³Lilly Research Laboratories, Indianapolis, Indiana, USA

12:48- 13:00 CLOSING CEREMONY & PRESENTATION OF AWARDS
Main Auditorium