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Slobodan Vukicevic (Zagreb, Croatia)

Bone morphogenetic proteins (BMPs)

Saturday 13 May 2006
13.00-14.00

Topics to be covered:

  • BMP protein receptors and their nuclear effectors in bone formation
  • BMPs in development
  • Clinical experience in regeneration of bone
  • Systemic administration of BMPs in restoring bone mass in mice and rats

 

Educational goals:

To discuss BMP biology related to the following issues

  • Can we biologically regenerate bone when normal physiological repair mechanisms fail?
  • BMP- as the first approved recombinant protein for treating long bone non-unions, spinal fusions and acute fractures
  • Deciphering the binding code of BMP-receptor interaction
  • The role of BMPs in the development of joints and segmentation of articular cartilage

 
Target audience

  • experts in the field of bone regeneration and repair
  • undergraduate students and postdoctoral fellows in skeletal biology
  • clinicians dealing with local and systemic regeneration of bone

 

Teaching methods

Topics will be covered by simple poster(s) containing important data
Principals of structure/function analysis will be discussed on flip chart drawings.
The audience will be involved by asking their opinion on various aspects of basic and clinical science of bone formation and regeneration.

 

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