Gudrun Stenbeck studied chemical engineering at undergraduate level and received her PhD from the Technical University Darmstadt, Germany, after PhD work on vesicular coat proteins in the laboratory of Prof Felix Wieland at the University of Heidelberg. She then undertook postdoctoral work with Prof James E. Rothman at the Memorial Sloan Kettering Cancer Center in New York before joining the laboratory of Prof Mike Horton at University College London to study the molecular mechanisms of osteoclastic bone resorption. She was awarded a prestigious Arthritis Research UK Fellowship in 2000 to establish her independent research laboratory. She is now a Senior Lecturer in Biomedical Sciences at Brunel University in London, UK and Head of the Bone Dynamics Laboratory.
Her research focuses on the cell biology of bone homeostasis and extracellular matrix deposition. Her current research is aimed at characterising the signalling events relaying extracellular stimuli to components of the intracellular trafficking machinery, with the ultimate aim of developing new strategies for the treatment of osteoarthritis, osteoporosis and fibrotic diseases. A distinct, yet complementary research line of her laboratory focusses on the intracellular fate of nanotherapeutics with the aim of establishing a possible link between endocytosed material and elicited immune responses, which may have a major impact on the biosafety of these novel therapeutics. Her research has been funded by Arthritis Research UK, the Royal Society and the Welcome Trust.
She also teaches cell biology and biochemistry at both undergraduate and postgraduate levels.