Insights from ERC Advanced Grant winner on bone biomechanics and career development
Live Webinar: 12 November 2019, 4pm-5pm CET
Content:
In this exciting webinar Professor Müller will provide an overview of his winning ERC advanced grant research as well as an interactive session on career advice for young scientists, which will get started with an interview by post-doctoral fellow Dr. Theresa Burkard. We encourage all scientists, junior and senior, to attend and interact in the webinar as there is something for all career stages.
Format:
- 25 min science presentation
- 10 min presentation of the career path
- 25 min Q&A
About the speaker:
Professor Ralph Müller, Head Laboratory for Bone Biomechanics at the ETH Zurich, has received an Advanced Grant of the European Research Council (ERC) for his MechAGE project. With that grant, the ERC is financing Müller’s research on in vivo single-cell mechanomics of bone adaptation and regeneration in the aging mouse.
MechAGE aims to investigate how mechanical vibrations influence bone development, adaptation and regeneration, which cell types are involved in these processes and how these cells react to age-related change. Specifically, Müller wants to use genome sequencing of single cells to understand how molecular ageing processes under mechanical loads affect bone remodeling. In the future, this understanding may facilitate targeted exercise programs within the context of personalized medicine to prevent osteoporosis-related bone fractures or heal them more quickly.
Throughout his career professor Müller has pioneered microtomographic imaging (microCT) of biological tissues both in vitro and in vivo, a technology that has been commercialized as a spin-off from ETH Zurich in the mid-1990s and is now successfully used in hundreds of laboratories and companies around the globe for research and development. The research the Laboratory is currently pursuing employs state-of-the-art biomechanical testing and simulation techniques as well as novel bioimaging and visualization strategies for musculoskeletal tissues. These approaches are now often used for precise phenotypic characterization of tissue response in mammalian genetics, mechanobiology as well as tissue engineering and regenerative medicine (www.bone.ethz.ch).
