PhD Training Oxford, UK 2 – 5 July 2009
ECTS PhD Training Course
2-5 July 2009
St Catherine’s College, Oxford,UK
Many thanks are extended to all who participated in another successful PhD training course which was held in Oxford, UK 2-5 July 2009.
Speaker Slides
Other bone diseases – Juliet Compston (Cambridge, UK)
Pharmacological manipulation of osteoclasts – Frazer Coxon (Aberdeen, UK)
Bone metabolism and calciotropic hormones – Richard Eastell (Sheffield, UK)
Interaction between bone and the central nervous system – Forent Elefteriou (Nashville, USA)
Bone cell signaling: In sickness and in health – Aymen Idris (Edinburgh, UK)
The ubiquitin proteasome system in bone biology – Rob Layfield (Nottingham, UK)
Osteoblasts – Pierre Marie (Paris, France)
Cadherin-Wnt interaction – Pierre Marie (Paris, France)
Biomechanics and mechanobiology of bone – Tim Skerry (Sheffield, UK)
Epigenetics – Rahul Tare (Southampton, UK)
Osteoclasts – Anna Teti (L’Aquila, Italy)
gp130 signalling in bone cell biology – Nathalie Sims (Melbourne, Australia)
PPARgamma. – Hans van Leeuwen (Rotterdam, The Netherlands)
Programme
Thursday July 2nd
Introductory session
14.00 Osteoclasts – Anna Teti (L’Aquila, Italy)
14.30 Osteoblasts – Pierre Marie (Paris, France)
15.00 Bone metabolism and calciotropic hormones – Richard Eastell (Sheffield, UK)
15.45 Coffee
16.15 Osteoporosis – Bente Langdahl (Aarhus, Denmark)
16.45 Other bone diseases – Juliet Compston (Cambridge, UK)
17.30 Break
17.45 Creative writing – Rebecca Abrams (Oxford, UK)
19.00 Dinner
Friday July 3rd
8.30 Session 1:
Stem cells and bone regeneration – Paolo Bianco (Rome, Italy)
9.15 Fracture healing and pharmacological manipulation thereof – Peter Schwarz (Copenhagen, Denmark)
10.00 Coffee
10.30 Session 2:
Biomechanics and mechanobiology of bone – Tim Skerry (Sheffield, UK)
11.15 Sclerosing bone disorders –Stuart Ralston (Edinburgh, UK)
12.00 Students’ presentations
5 minutes each
Mr Hermann Agis Vienna, Austria
Cellular mechanisms of guided bone regeneration: The impact of platelets and biomaterials in vitro
Dr Nerea Alonso Lopez Edinburgh, UK
Phenotypic characterisation of RANK mutation knock-in mice
Dr Elisa Benasciutti Milan, Italy
Mouse genetics models reveal MHC class II transactivator as a novel regulator of osteoclastogenesis and bone homeostasis co-opted from adaptive immunity
Mr Mattia Capulli L’Aquila, Italy
Mechanisms of bone remodeling regulated by mechanical forces
Jana Dragojevic Ljubljana, Slovenia
The role of PPARX in bone metabolism
Miss Katarzyna Gurzawska Copenhagen, Denmark
Coating of bone implants
Mr El Mustapha Haddouti Bonn, Germany
Mesenchymal stem cells potential in tissue engineering for bone regeneration
12.45 LUNCH
13.45 Students’ presentations (cont)
5 minutes each
Dr Jannie Dahl Hald Aarhus, Denmark
Osteogenesis Imperfecta – genetics, phenotype and medical treatment
Dr Torben Harsløf Aarhus, Denmark
The role of peroxisome proliferator-activated receptor gamma and its ligands in osteoporosis
Liesbet Lieben Leuven, Belgium
1,25OH2D3 signaling in the intestine and bone
Katie Marchbank London, UK
Role of Nbr1 in bone remodeling
Dr Silvia Marino Orbassano, Italy
Pharmacological treatment of bone fracture healing
Mr David Mellis Aberdeen, UK
To study the cellular and molecular mechanisms behind Paget’s Disease of Bone caused by mutations in the RANK gene
Miss Martiene Moester Leiden, The Netherlands
Modulation of sclerostin expression in osteoporosis
15.00 Coffee
15.30 Session 3: Techniques
PPARgamma.- Hans van Leeuwen (Rotterdam, The Netherlands)
16.15 Cadherin-Wnt interaction – Pierre Marie (Paris, France)
17.00 End of day
19.00 Dinner
Saturday July 4th
8.30 Session 4:
Interaction between bone and fat tissue – Moustapha Kassem (Odense, Denmark)
9.15 Interaction between bone and the central nervous system – Forent Elefteriou (Nashville, USA)
10.00 Coffee
10.30 Session 5:
Epigenetics – Rahul Tare (Southampton, UK)
11.15 gp130 signalling in bone cell biology – Nathalie Sims (Melbourne, Australia)
12.00 Students’ presentations
5 minutes each
Mrs Kristine Møller Aarhus, Denmark
Calcium homeostasis and bone metabolism during pregnancy and lactation
Mrs Priscilla Morethson São Paulo, Brazil
Proton and chloride transport in primary rat osteoclasts: effects of alendronate and calcitonin
Brian Nicholls London UK
The role of AKT in mediating the adaptive response of osteoblasts in mechanical strain
Miss Pamela Pail Vienna, Austria
Mechanisms of osteoblast-osteoclast signalling
Miss Lianne Reddie Manchester, UK
The metaphyseal index as a tool for the assessment of distal radius development
Dr Roberta Scianaro Rome, Italy
Role of the immune system in bone resorption: does the mineralized matrix induce an osteoclast-activating “danger signal”?”
Amir-Shaya Sharili London, UK
The role of the transcription factor snail 2 in bone cancer and repair
12.45 LUNCH
13.45 Students’ presentations (cont)
5 minutes each
Ms Tanja Tvistholm Sikjaer Aarhus, Denmark
Treatment of hypoparathyroidism with subcutaneous PTH 1-84 injections: effects on muscle function and quality of life
Miss Katherine Staines Midlothian, Scotland
Unravelling the regulatory mechanisms controlling inorganic phosphate mobilisation during growth plate mineralisation and bone development
Ms Susanna við Streym Thomsen Horsens, Denmark
Fetal status of Vitamin D – a risk factor for disease?
Dr Karolina Turzanska Lublin, Poland
Bioavailability of Strontium administered orally to growing mice as ranelate versus chloride
Mrs Karen van der Meijden Utrecht, The Netherlands
Extrarenal hydroxylation of 25-hydroxyvitamin: stimulation by 25-hydroxyvitamin D and by mechanical forces.
Dr Martina Winkler-Krottmaier Vienna, Austria
Characterization and assessment of risk factors of hip fracture patients
Mrs Elisabeth Ytteborg Ås Norway
Characterization of mechanisms involved in development of vertebral deformities in Atlantic salmon Salmo salar
15.00 Coffee
15.30 Session 6: Animal models
Quantification of gene expression – Alun Hughes (Aberdeen, UK)
Structure and mineralisation of bone and cartilage – Alan Boyde (London, UK)
16.15 Structure and mineralisation of bone and cartilage – Alan Boyde (London, UK)
End of day
19.00 Dinner
Sunday July 5th
9.00 Session 7:
Assessment of fracture risk – Eugene McCloskey (Sheffield, UK)
09.45 The ubiquitin proteasome system in bone biology – Rob Layfield (Nottingham, UK)
10.30 Coffee
11.00 Session 8:
Pharmacological manipulation of osteoclasts – Frazer Coxon (Aberdeen, UK)
11.45 Bone cell signaling: In sickness and in health – Aymen Idris (Edinburgh, UK)
12.45 Lunch
13.45 Adjourn