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ECTS PhD TRAINING 13–16 September 2015

Local Organiser: Cristina Sobacchi

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Thank you to everyone who participated in our 9th PhD Training Course in Siena.

Programme

Sunday 13th September
15:00-15:15 Introduction to the Course
Gudrun Stenbeck (London, UK)
15:15-16:00 Bone Cells: Osteoblasts
Hans van Leeuwen (Rotterdam, NL)
16:00-16:45 Bone Cells: Osteocytes
Jenneke Klein-Nuland (Amsterdam, NL)
16:45-17:00 Coffee Break
17:00-17:45 Bone Cells: Osteoclasts
Anna Teti (Rome, Italy)
17:45-18:30 Gene and epigenetic editing for the treatment of monogenic diseases
Angelo Lombardo (Milan, Italy)
18:30 End of Day
19:15 Dinner
20:30 Speed Mentoring
Monday 14th September
09:00-09:45 Osteoporosis
Bente Langdahl (Aarhus, Denmark)
09:45-10:30 BMD and fracture risk association
Jennifer Walsh (Sheffield, UK)
10:30-11:15 Hormone Replacement Therapy
Luigi Gennari (Siena, Italy)
11:15-11:35 Coffee Break
11:35-13:00 Student Presentations
13:00-14:00 Lunch
14:00-14:45 Bone research in context: zebrafish as model organism
Ann Huysseune (Ghent, Belgium)
14:45-15:30 Vascular Calcification in Chronic Kidney disease
Cathy Shannahan (London, UK)
15:30-16:15 Circadian Clocks in Age Related Diseases
Qing-Jun Meng (Manchester, UK)
16:15-18:00 Structured poster viewing
18:00 End of Day
19:00 Dinner
20:00 Fire place discussion: The next stages of your career
Tuesday 15th September
09:45-10:30 Rare Bone Diseases
Cristina Sobacchi (Milan, Italy)
10:30-11:15 Skeletal Stem Cells
Paolo Bianco (Rome, Italy)
11:15-11:45 Coffee Break
11:45-12:30 Insulin and Bone
Colin Farquharson (Edinburgh, UK)
12:30-14:15 Lunch
14:15-16:00 Student Presentations
16:00-16:30 Coffee Break
16:30-18:00 Workshops
Translating science into effective medicine Clinical Trial Design
Paolo Bianco (Rome, Italy) Jennifer Walsh (Sheffield, UK)
18:00 End of Day
19:00 Dinner
Wednesday 16th September
09:00-09:45 Osteoimmunology
Claudine Blin (Nice, France)
09:45-10:30 Immunsystem and Fracture Healing
Anita Ignatius (Ulm, Germany)
10:30-10:45 Coffee Break
10:45-11:30 Stem cell transpantation in bone and cartilage disorders
Antonella Forlino (Pavia, Italy)
11:30-12:15 Animal Models for Cartilage Repair
Giuseppe Perettti (Milan, Italy)
12:15-12:30 Concluding Remarks
Gudrun Stenbeck (London, UK)

Sponsorship

The ECTS PhD Training Programme was supported by ECTS Corporate Members; Amgen, Eli Lilly and Alexion, who offer year-round support for all ECTS activities. We would like to extend our thanks to all of our partners for their support for this key educational activity.

ECTS PhD TRAINING 2-5 July 2016

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Thank you to all speakers and delegates who attended the ECTS PhD Training Course in Oxford and contributed to another successful event.

 

PROGRAMME

SPEAKER PROFILES: PhD TRAINING, MolPharm

 

SATURDAY JULY 2
11:30 REGISTRATION OPEN – Mary Sunley Building
12:45 Lunch – Dining Hall
13:30-13:45 Introduction  – Astrid Bakker (Amsterdam, Netherlands)
13:45-14:30 Cell biology of bone – Gudrun Stenbeck (London, UK)
14:30-15:15 Clinical aspects of bone biology – Bente Langdahl (Aarhus, Denmark)
15:15-15:30 Break
15:30-16:15 The Wnt pathway – Astrid Bakker (Amsterdam, Netherlands)
16:15-17:00 Creating a good research question – Kassim Javaid (Oxford, UK)
17:00-17:10 Break and move to Bernard Sunley Building
17:10-18:10

JOINTLY WITH MOLECULAR PHARMACOLOGY WORKSHOP

Bernard Sunley Building
17:10 Musculoskeletal research in Oxford – Graham Russell (Oxford, UK)
 17:15 Changing paradigms in osteoarthritis – Tonia Vincent (Oxford, UK)
 17:30  Keynote lecture
Rare diseases: the scope, opportunities and regulatory aspects – Matt Warman (Boston, USA)
19:00 Dinner – Dining Hall
20:00 Speed mentoring
SUNDAY JULY 3
8.00 Breakfast – Dining Hall
PhD Sessions – Mary Sunley Building
9:15-10:00 Role of inflammation in tendinopathies – Stephanie Dakin (Oxford, UK)
10:00-10:15 Break
10:15-11:00 Analysis of bone phenotypes in mouse models of skeletal disease, Duncan Bassett (London, UK)
11:00-11:45 SEM/TEM in bone – Miep Helfrich (Aberdeen, UK)
11:45-12:45 Optimizing data analysis – Kassim Javaid (Oxford, UK)
12:45-13.30 Lunch – Dining Hall
13:30-15:00 Facilitated student group workshop: applying lectures to your own research plan (3 groups: basic, cellular, clinical)
15:00-15:30 Break – Move to Bernard Sunley Building
15:30 – 18.00

JOINTLY WITH MOLECULAR PHARMACOLOGY WORKSHOP

Bernard Sunley Building
THERAPEUTIC DIRECTIONS IN RARE GENETIC DISEASES
15.30 Introduction and update on osteogenesis imperfecta – Francis Glorieux (Montreal, Canada)
15.50 Genetic approaches to identifying drug targets: ENU mutagenesis in skeletal research – Paul Potter (Harwell, UK)
16.10 Enzyme replacement therapy: lessons from hypophosphatasia in childhood – Michael Whyte (St Louis, USA)
16.30 Mineralization defects in neurofibromatosis type 1 and therapeutic implications –  Florent Elefteriou (Houston, USA)
16.50 Novel approaches to treating rare bone diseases – Melita Irving (London, UK)
17.10 Break
17.20 Keynote lecture
Oxygen sensing in animal cells: a new therapeutic opportunity? – Peter Ratcliffe (Oxford)
18:00-19:00 Poster viewing  – Junior common room bar annex
PRESENTATIONS – ODD NUMBERS
19:00 Dinner – Dining Hall
MONDAY JULY 4
08:00 Breakfast – Dining Hall
PhD Sessions – Mary Sunley Building
8:45-9:30 Cancer and bone – Larry Suva (Little Rock, USA)
9:30-10:15 The hypoxic cancer secretome – Alison Gartland (Sheffield, UK)
10:15-10:30 Break
10:30-13:00 Student presentations (final year)
13:00-14:00 Lunch – Dining Hall
14:00-15:00 Facilitated student group workshop: data presentation: clinical versus basic with Q/A
15:10-15:30 Break – move to Bernard Sunley Building
15:30-17:10

JOINTLY WITH MOLECULAR PHARMACOLOGY WORKSHOP

Bernard Sunley Building
HIGHLIGHTS IN BONE BIOLOGY AND DISEASEDISEASES
 15:30 Introduction: historical perspective – John Potts (Boston, USA)
15:40 Recent insights into PTH action and therapeutic potential – Hank Kronenberg (Boston, USA)
16:10 Update on paget’s disease: genetics and treatments – Stuart Ralston (Edinburgh, UK)
16:40 Challenges in pain research: angiotensin ii type 2 receptor antagonists: pain relief & beyond – Tom McCarthy (Oxford, UK)
17:00 Break
17:05 Keynote lectures:

  • Genetics, epigenetics and the microbiome – Tim Spector (London, UK)
  • Strategies for enhancing drug discovery – Chas Bountra (Oxford, UK)
18:00-19:00 Poster viewing – Junior common room bar annexPRESENTATIONS – EVEN NUMBERS
19:00 Dinner – Dining Hall
20:15 Oxford by night – Informal Walking Tour – meet at Porters Lodge
TUESDAY JULY 5
08:00 Breakfast – Dining Hall
9:00– 10:30 Student group presentations of research projects developed during the course
10:30-10:45 Break
10:45-11:45 Student group presentations of research projects developed during the course (continued)
11:45-12:00 Concluding remarks – Astrid Bakker (Amsterdam, Netherlands)
12:00 End of course 
12:55 Lunch for pre-booked students who are joining the Molecular Pharmacology Workshop
14:00 Molecular Pharmacology Workshop Sessions – Bernard Sunley Building