Topic: Hereditary Multiple Echondromen
Organised by the Rare bone diseases action group
Chair: Prof. dr. Natasha Appelman-Dijkstra, Leiden University Medical Center, Leiden, Netherlands
Speakers: Dr. Alice Moroni, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy and Marina Mordenti, PhD, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Date & Time: Thursday, 18 December 2025 from 16.00-17.00hrs CET
Format: Live Interactive Webinar. On-demand recording to be available for ECTS full tier members after the event

Registration

The live webinar is free and open to everyone with an interest in the field.

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Agenda:

Introduction by Prof.dr. Appelman-Dijkstra (3 min)
Presentation on “Hereditary Multiple Echondromen” by Dr. Moroni and Dr. Mordenti (40 min)
Live Q&A from the audience, moderated by Prof.dr. Appelman-Dijkstra (15 min)
Conclusion and key messages by Prof.dr. Appelman-Dijkstra (2 min)

Topic: Early-Onset Osteoporosis: Genetics, Filtering, and Functional Modelling
Organised by the Rare bone diseases action group
Chairs: Dr Adalbert Raimann, Medical University of Vienna, Vienna, Austria and Dr Felix von Brackel, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
Speakers: Pr Dr Melissa Formosa, University of Malta, Msida, Malta and Pr Dr Ralf Oheim, University Medical Center Hamburg, Hamburg, Germany
Date & Time: Thursday, 16 October 2025 from 16.00-17.00hrs CET
Format: Live Interactive Webinar. On-demand recording to be available for ECTS full tier members after the event

Registration

The live webinar is free and open to everyone with an interest in the field.

Register

Learning objectives:

• Describe the key steps in analysing early-onset osteoporosis, from recruitment and deep phenotyping to sample collection and data preparation.
• Understand the application of high-throughput sequencing coupled with stepwise variant filtering strategies to identify potential causal genetic factors.
• Assess the translational value of genetic findings through functional studies in cellular and animal models.

Agenda:

Introduction by Dr von Brackel (3 min)
Presentation on “Early-Onset Osteoporosis: Genetics, Filtering, and Functional Modelling” by Pr Dr Formosa and Pr Dr Oheim (40 min)
Live Q&A from the audience, moderated by Dr Raimann (15 min)
Conclusion and key messages by Dr Raimann (2 min)

Topic: Hyperphosphatemic familial tumoral calcinosis (HFTC)
Organised by the Rare bone diseases action group
Chairs: Pr Natasha Appelman-Dijkstra, Leiden University Medical Center, Leiden, The Netherlands
Speaker: Dr Kelly Roszko, National Institutes of Health, USA
Date & Time: Thursday, 21 August 2025 from 16.00-17.00hrs CET
Format: Live Interactive Webinar. On-demand recording to be available for ECTS full tier members after the event

Registration

The live webinar is free and open to everyone with an interest in the field.

Register

Agenda:

• Introduction by Pr Appelman-Dijkstra (3 min)
• Presentation on “Hyperphosphatemic familial tumoral calcinosis (HFTC)” by Dr Roszko (40 min)
• Live Q&A from the audience, moderated by Pr Appelman-Dijkstra (15 min)
• Conclusion and key messages by Pr Appelman-Dijkstra (2 min)

Topic: Analytical tools for characterization of advanced glycation endproducts in bone
Organised by the ECTS E-learning action group
Chairs: Pr Dr Petar Milovanovic, Center of Bone Biology, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
Speaker: Ass Pr Eve Donnelly, Materials Science, Cornell University, New York, USA
Date & Time: Thursday, 24 July 2025 from 16.00-17.00hrs CET
Format: Live Interactive Webinar. On-demand recording to be available for ECTS full members tier after the event

Registration

The live webinar is free and open to everyone with an interest in the field.

Learning objectives:

1. Describe advanced glycation endproducts (AGEs) and the mechanisms by which they form in connective tissues.
2. Identify the techniques currently available for assessment of AGEs in bone and the main outcomes of each method.
3. Discuss the relative strengths and limitations of these methods.
4. Identify knowledge gaps that would inform clinical utilization and improve patient care.

Agenda:

• Introduction by Pr Dr Milovanovic (3 min)
• Presentation on “Advanced Glycation End-products (AGEs) induce bone fragility” by Ass Pr Donnelly (30 min)
• Live Q&A from the audience, moderated by Pr Dr Milovanovic (25 min)
• Conclusion and key messages by Pr Dr Milovanvic (2 min)

Topic: Ollier disease
Organised by the Rare bone diseases action group
Chairs: Pr Thomas Funck-Brentano, Laboratoire Bioscar, INSERM, Paris, France and Dr Charlotte Verroken, University of Ghent, Ghent, Belgium
Speaker: Dr Nara Sobreira, Johns Hopkins University, Maryland, USA
Date & Time: Thursday, 19 June 2025 from 16.00-17.00hrs CET
Format: Live Interactive Webinar. On-demand recording to be available for ECTS full tier members after the event

Registration

The live webinar is free and open to everyone with an interest in the field.

Learning objectives:

1 – Discuss the phenotypic presentation of Ollier disease and Maffucci syndrome

2 – Discuss the genetic etiology of Ollier disease and Maffucci syndrome

3 – Discuss the differential diagnosis of Ollier disease and Maffucci syndrome

Agenda:

Introduction by Pr Funck-Brentano  (3 min)
Presentation on “Ollier disease” by Dr Sobreira (40 min)
Live Q&A from the audience, moderated by Pr Funck-Brentano and Dr Verroken (15 min)
Conclusion and key messages by Dr Verroken (2 min)