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Webinar Bone, Muscle & Beyond: Bone and muscle cross talk in bone repair  

Date & Time: 20 October 2022, 4 pm CET

Featuring Céline Coltnot and Moderated by Jessica Pepe

Format:

  • 5 min welcome & introductions
  • 35 min presentation
  • 20 min Q&A

Followed by a Coffee Shop

Learning Objectives:

During this webinar, the speaker will review:

  • The ability to repair itself is an important function of adult bone and is dependent on the proliferation and differentiation of skeletal stem/progenitor cells. 
  • The contribution of local versus systemic sources of skeletal stem cells. 
  • To elucidate the mechanisms of stem cell activation in their complex tissue environment in development, disease and repair.

Costs: Live webinar is free for ECTS members and non-members, but a registration is required. Recordings are accessible to ECTS members only.

REGISTER

 

About the Speaker

Céline Colnot

I am currently a Director of Research, DR2 INSERM, at Mondor Institute for Biomedical Research, Créteil. I completed my PhD in Paris in 1998 and my postdoctoral training at University of California, San Francisco where I became Assistant Professor until 2010. My research concentrates on the biology of skeletal stem cells that are the basis for the high regenerative capacities of skeletal tissues and that are potentially deficient in various musculoskeletal diseases and disorders. I received continuous funding since 2005 from NIH, European Marie Curie Program and the French National Research Agency. The projects of my research team aim to elucidate the mechanisms of stem cell activation in their complex tissue environment in development, disease and repair employing genetic mouse models, genomics and cellular approaches. We focus on the periosteum, the tissue at the outer surface of bone and skeletal muscle adjacent to bone, that also plays essential roles in bone regeneration. The ATIP-AVENIR funding was key for us to accomplish the characterization skeletal stem cells within periosteum. These results are now the bases for several other projects further exploring periosteum functions in bone repair and its interactions with skeletal muscle, the vasculature and the nervous system.

Webinar Bone, Muscle & Beyond: Relationship between the nervous system and the skeleton  

Date & Time: 15 September 2022, 4-5 pm CEST, followed by 15 minutes of interactive discussions in a Coffee Shop style

Organised by the European Calcified Tissue Society (ECTS) in collaboration with the International Society of Bone Morphometry (ISBM)

Featuring Dr Erica Scheller, DDS, PhD & moderated by Dr Maria-Bernadette Madel

Format:

  • 5 min welcome & introductions
  • 35 min presentation
  • 20 min Q&A
  • 15 min Coffee Shop

Learning objectives:

  • Define the distribution and morphology of nerves within the skeletal system.
  • Summarize the relationship between peripheral neuropathy and skeletal disease. 
  • Develop future directions and hypotheses related to the function of nerves in bone. 

Costs: Live webinar is free for ECTS members and non-members, but a registration is required. Recordings are accessible to ECTS members only.

WATCH RECORDINGS

 

About the Speaker

Erica Scheller, DDS, PhD

Dr. Scheller is an Assistant Professor of Medicine at Washington University in Saint Louis and the current president of the International Society of Bone Morphometry (ISBM). Her research background spans the fields of bone biology, neurobiology, and integrated physiology. The Scheller Lab has a directed interest in leveraging high-resolution imaging techniques and in vivo models to study the bidirectional communication between the nervous system and the skeletal microenvironment.

@schellerlab  @ISBM_society

Webinar Bone, Muscle & Beyond: Diversity and immune function of osteoclasts  

Date & Time: 18 August 2022, 4 pm CET

Featuring Claudine Blin and moderated by Maria-Bernadette Madel

Format:

  • 5 min welcome & introductions
  • 35 min presentation
  • 20 min Q&A
  • 15 min Coffee Shop for more interactive and informal discussions

Learning objectives:

  • The principles of the connection between the bone and the immune system.
  • The principles of monocytic cell function
  • How to understand diversity within a cell population

Followed by a Coffee Shop

Costs: Live webinar is free for ECTS members and non-members, but a registration is required. Recordings are accessible to ECTS members only.

WATCH RECORDINGS

 

Faculty:

Claudine Blin

Claudine Blin is research director and head of the team “Osteoimmunology, Niches and Inflammation” at the Laboratory of Molecular Physiomedicine, Nice, France. She obtained her PhD from the University Paris Diderot in 1995. In 2003, she established her independent research group on osteoimmunology in Nice. Her team projects are at the interface between osteology, immunology and stem cell biology, mostly in the context of chronic inflammatory diseases. She has a special interest in the heterogeneity and innate immune function of osteoclasts, their interaction with immune cells, and their contribution in inflammatory bone destruction. Claudine Blin has been secretary and is president elect of the French Society of Mineral Tissue Biology (SFBTM) and member of the ECTS Board of Directors. She is also a member of the scientific board of the French Arthritis Fondation and a member of the scientific and educational committee of the Life University School of Research, University Cote d’Azur.

Webinar Bone, Muscle & Beyond: Atypical femur fractures – genetic background and treatment dilemma’s

Date & Time: 21 July 2022, 4 pm CET

Featuring Prof Carola Zillikens

Format:

  • 5 min welcome & introductions
  • 35 min presentation
  • 20 min Q&A

Followed by a Coffee Shop

Costs: Live webinar is free for ECTS members and non-members, but a registration is required. Recordings are accessible to ECTS members only.

WATCH RECORDINGS

 

Faculty:

Featuring Dr Carola Zillikens

Carola Zillikens, MD, PhD, is Professor and staff member at the Department of Internal Medicine, section Endocrinology, of Erasmus MC,

University Medical Center Rotterdam, the Netherlands. She founded and heads the Erasmus MC Bone Center, a multidisciplinary

expertise center for patients with common and rare disorders of calcium and bone metabolism. She is past President of the Dutch Society

for Calcium and Bone Metabolism and a past Board Member of ECTS (2015-2021) where she chaired the Professional Practice Committee. She is a member of the Steering committee of the European Reference Network for rare bone disorders, BOND since 2015. Her research topics concern the (genetic) background of unexplained familial osteoporosis, rare disorders of calcium, phosphate and bone metabolism, atypical femur fractures and the relation of osteoporosis with chronic diseases and mortality and the role of Advanced Glycation End products (AGEs) in this association. She is coordinating a Dutch national registry for chronic hypophosphatemia, including XLH. She has co-authored over 260 papers.

 

 

Webinar Bone, Muscle & Beyond: Exploring the interface between inflammatory and glucocorticoid induced bone loss 

Date & Time: 19 May 2022, 4 pm CET

Featuring Dr Rowan Hardy and Chaired by Dr Lars Folkestad

Format:

  • 5 min welcome & introductions
  • 35 min presentation
  • 20 min Q&A
  • 15 min coffee shop

Learning objectives:

  • Understand mechanisms of inflammatory bone loss 
  • Understand mechanisms of glucocorticoid induced osteoporosis
  • Appreciate how inflammation and therapeutic glucocorticoids interact to regulate bone metabolism
  • Understand the role that steroid metabolism plays in these processes

Costs: Live webinar is free for ECTS members and non-members, but a registration is required. Recordings are accessible to ECTS members only.

Watch Recordings

 

 

Faculty:

Featuring Dr Rowan Hardy

Rowan Hardy is a Versus Arthritis Fellow and Lecturer at the University of Birmingham with extensive experience in steroid metabolism and in vivo models of chronic inflammation. Patients with chronic inflammatory diseases develop systemic complications such as muscle wasting and bone loss, which contribute to disability and reduced life expectancy. His research group is examine the roles of myeloid and mesenchymal steroid metabolism and signalling in mediating inflammatory disease pathophysiology and systemic complications in muscle and bone, identifying novel strategies to improve the safety profile of therapeutic glucocorticoids. The inter-disciplinary collaboration linking the Institute of Metabolism & Systems Research and Inflammation & Ageing ensure a fully translational approach to this research, utilising state of the art cell culture, molecular biology and animal husbandry facilities.